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is there a herpes vaccine1337 .pdf


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is there a herpes vaccine
People who are aware of the herpes simplex virus would like to have a herpes vaccine available
for protection. Those who already contracted the virus would like a vaccine to get cured. Until
now, a herpes vaccine does not exist. If you have heard about it, that is because it is in
development since long time already.
There is a controversy regarding who would benefit from a herpes vaccine. As you know,
vaccines are often used to prevent disease, not once it has been contracted. In this case
immunization no longer works. Instead, research would have to be done to find a cure.
Certainly, a herpes vaccine would be indicated for people who want further protection in the case
practicing safe sex fails, people who have a partner that may be unfaithful, and couples with one
partner who is diagnosed with herpes. However, a few sources mention that those who already
have the virus will also benefit at least in some way.
Pharmaceutical companies have tested other vaccines to find out if they can do any good in
herpes. After all, they have been already developed. These vaccines are Smallpox, Polio and
Lupidon C. So far, they have had no measurable effects. That is why Pharmaceutical companies
considered the need to develop a herpes vaccine.
Glaxosmithkline Biologicals began the Herpevac trial for women involving 8,323 women that
concluded in 2010. In 2 earlier trials involving fewer men and women who tested negative for
genital herpes but whose sexual partners were known to be infected, Herpevac demonstrated
over 70% efficacy in women but was unable to protect men. A subsequent, larger trial, found that
this herpes vaccine candidate had some efficacy against oral herpes but not against genital
herpes.
Agenus and a Sanofi-NIH collaboration announced the phase II trial for their HerpV, another
herpes vaccine candidate, involving 80 patients. Following a series of vaccinations and a booster
dose at 6 months, most patients showed an immune response. This herpes vaccine candidate
reduced the viral load by 75%, which has the potential to reduce the incidence and severity of
outbreaks as well as reduce its transmission.
Instead of holding on to the idea of a herpes vaccine, doctors are considering alternative
management methods such as immunotherapy and antiviral therapy. The former consists on
developing substances that stimulate the immune system so that it fights the virus through natural
processes. The latter consists on the development of drugs that can distinguish the cells that
carry the virus and destroy it without leaving fragments or producing mutations that may resurface
in the infected cells.
Isoniplex is an antiviral drug and immunopotentiator in viral diseases that compensates for the
lack of a herpes vaccine. This drug became approved in over 56 countries but not in the US.
Isoniplex takes effect on both oral and genital herpes.

A herpes vaccine has not been developed yet. There are people who have a different disease
known as herpes zoster or shingles, a painful skin rash caused by the varicella zoster virus. A
vaccine for it was developed since long ago. It is recommended that people aged 60 or above get
it because the risk of getting the zoster virus increases with age. Even those who have had it can
receive the vaccine to prevent future outbreaks.
What causes herpes? Learn more regarding the herpes disease.


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