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CURRICULUM VITAE:
Sokbom Kang, M.D., Ph.D.
Updated: 2011-7-12
Director, Division of Gynecologic Oncology Research
National Cancer Center
Ilsan-gu, Madu-dong
Goyang, 410-769, Republic of Korea

EDUCATION
Dates
Attended

Institutions

Degrees/

1989-1995

Seoul National University,
College of Medicine, Seoul, Korea

B.S.

1995-1996

Seoul National University hostpital,
Seoul, Korea

Intern

1996-2000

Seoul National University hostpital,
Seoul, Korea

Resident

Obstetrics and
Gynecology

2003-2005

Seoul National University hospital,
Seoul, Korea

Fellow

Gynecologic
Oncology

2003-2005

Seoul National University,
College of Medicine, Seoul, Korea

M.S.

Gynecologic
Oncology

2005-2007

Seoul National University,
College of Medicine, Seoul, Korea

Ph.D.

Gynecologic
Oncology

Title or status

CERTIFICATIONS
2000~

Korean Board of Obstetrics and Gynecology

PRINCIPAL POSITIONS HELD
2005-2007 Surgeon, Uterine Cancer Center
National Cancer Center, Goyang, Republic of Korea
2007-2009 Senior Investigator and Surgeon,
Division of Gynecologic Oncology Research
National Cancer Center, Goyang, Republic of Korea
2009~

Director, Division of Gynecologic Oncology Research
National Cancer Center, Goyang, Republic of Korea

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Major
subjects
Medicine

AWARDS AND HONORS
2004

Scholar-in-training award, The 95th AACR annual meeting
American Association of Cancer Research (AACR)

2004

Scholar-in-training award, The 3rd AACR Frontiers in Cancer Prevention Research,
American Association of Cancer Research (AACR)

2005

Scholar-in-training award, The 4th AACR Frontiers in Cancer Prevention Research,
American Association of Cancer Research (AACR)

2005

S.S.Ratnam - Young Gynaecologist Award,
Asia & Oceania Federation of Obstetrics & Gynaecology (AOFOG)

2009

2009 JGO contribution award, Korean Society of Gynecologic Oncology

2010

2010 JGO contribution award, Korean Society of Gynecologic Oncology

2010

2010 Research excellence award, National Cancer Center

2011

2011 JGO contribution award, Korean Society of Gynecologic Oncology

2011

2011 Research excellence award, National Cancer Center

PROFESSIONAL ORGANIZATIONS
Major Committee Assignments
Korean Society of Gynecologic Oncology and Colposcopy
Member

2003-present

Scientific Review Committee

2006-present

Scientific Advisory Committee

2010-present

2007 AOGIN Scientific Program Committee

2007

2011 ASGO Scientific Program Committee

2010-present

Korean Gynecologic Oncology Group
Ovarian-fallopian tube Tumor Site Committee

2009-present

Secretary, Translational Research Committee

2006-present

PEER-REVIEWED JOURNAL PUBLICATIONS

Recent updates can be browsed at the following address:
http://www.ncbi.nlm.nih.gov/pubmed?term=Sokbom%20Kang

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1.
Song, Y. J., Lim, M. C., Kang, S., Seo, S. S., Kim, S. H., Han, S. S., and Park,
S. Y. Extended cytoreduction of tumor at the porta hepatis by an interdisciplinary team
approach in patients with epithelial ovarian cancer. Gynecol Oncol, 121: 253-7, 2011.
2.
Song, Y. J., Kim, J. Y., Lee, S. K., Lim, H. S., Lim, M. C., Seo, S. S., Kang,
S., Lee, D. O., and Park, S. Y. Persistent human papillomavirus DNA is associated with
local recurrence after radiotherapy of uterine cervical cancer. Int J Cancer, 129: 896-902,
2011.
3.
Rho, S. B., Lee, J. H., Park, M. S., Byun, H. J., Kang, S., Seo, S. S., Kim, J.
Y., and Park, S. Y. Anti-apoptotic protein TCTP controls the stability of the tumor
suppressor p53. FEBS Lett, 585: 29-35, 2011.
4.
Rho, S. B., Kim, B. R., and Kang, S. A gene signature-based approach
identifies thioridazine as an inhibitor of phosphatidylinositol-3'-kinase (PI3K)/AKT
pathway in ovarian cancer cells. Gynecol Oncol, 120: 121-7, 2011.
5.
Lee, C. H., Roh, J. W., Choi, J. S., Kang, S., Park, I. A., Chung, H. H., Jeon,
Y. T., Kim, J. W., Park, N. H., Kang, S. B., and Song, Y. S. Cyclooxygenase-2 is an
independent predictor of poor prognosis in uterine leiomyosarcomas. Int J Gynecol
Cancer, 21: 668-72, 2011.
6.
Kang, S., Park, J. Y., Lim, M. C., Song, Y. J., Park, S. H., Kim, S. K., Chung,
D. C., Seo, S. S., Kim, J. Y., and Park, S. Y. Pelvic lymph node status assessed by
18F-fluorodeoxyglucose positron emission tomography predicts low-risk group for
distant recurrence in locally advanced cervical cancer: a prospective study. Int J Radiat
Oncol Biol Phys, 79: 788-93, 2011.
7.
Kang, S., Kim, T. J., Seo, S. S., Kim, B. G., Bae, D. S., and Park, S. Y.
Interaction between preoperative CA-125 level and survival benefit of neoadjuvant
chemotherapy in advanced epithelial ovarian cancer. Gynecol Oncol, 120: 18-22, 2011.
8.
Kang, S., Kim, T. J., Seo, S. S., Kim, B. G., Bae, D. S., and Park, S. Y. Role
of Extended Chemotherapy in Advanced Ovarian Cancer Patients with High
Posttreatment Serum CA-125 Levels. Gynecol Obstet Invest, 2011.
9.
Kang, S., Jong, Y. H., Hwang, J. H., Lim, M. C., Seo, S. S., Yoo, C. W., and
Park, S. Y. Is Neo-adjuvant Chemotherapy a "Waiver" of Extensive Upper Abdominal
Surgery in Advanced Epithelial Ovarian Cancer? Ann Surg Oncol, 2011.
10.
Kang, S. Cervical adenocarcinoma in situ with negative conization margin:
negligible or not? J Gynecol Oncol, 22: 1-2, 2011.
11.
Hwang, J. H., Lim, M. C., Seo, S. S., Park, S. Y., and Kang, S. Phase II study
of belotecan (CKD 602) as a single agent in patients with recurrent or progressive
carcinoma of uterine cervix. Jpn J Clin Oncol, 41: 624-9, 2011.
12.
Choi, H. J., Lim, M. C., Bae, J., Cho, K. S., Jung, D. C., Kang, S., Yoo, C.
W., Seo, S. S., and Park, S. Y. Region-based diagnostic performance of multidetector CT
for detecting peritoneal seeding in ovarian cancer patients. Arch Gynecol Obstet, 283:
353-60, 2011.
13.
Park, B., Park, S., Kim, T. J., Ma, S. H., Kim, B. G., Kim, Y. M., Kim, J. W.,
Kang, S., Kim, J., Yoo, K. Y., and Park, S. K. Epidemiological characteristics of ovarian
cancer in Korea. J Gynecol Oncol, 21: 241-7, 2010.
14.
Lim, M. C., Song, Y. J., Seo, S. S., Yoo, C. W., Kang, S., and Park, S. Y.
Residual cancer stem cells after interval cytoreductive surgery following neoadjuvant

- 3 -

chemotherapy could result in poor treatment outcomes for ovarian cancer. Onkologie, 33:
324-30, 2010.
15.
Lim, M. C., Seo, S. S., Kang, S., Seong, M. W., Lee, B. Y., and Park, S. Y.
Hereditary non-polyposis colorectal cancer/Lynch syndrome in Korean patients with
endometrial cancer. Jpn J Clin Oncol, 40: 1121-7, 2010.
16.
Lim, M. C., Lee, H. S., Kang, S., Seo, S. S., Lee, B. Y., and Park, S. Y.
Minimizing tumor burden by extensive cytoreductive surgery decreases postoperative
venous thromboembolism in ovarian clear cell carcinoma. Arch Gynecol Obstet, 281:
329-34, 2010.
17.
Lim, M. C., Lee, B. Y., Lee, D. O., Joung, J. Y., Kang, S., Seo, S. S., Chung,
J., and Park, S. Y. Lower urinary tract injuries diagnosed after hysterectomy: seven-year
experience at a cancer hospital. J Obstet Gynaecol Res, 36: 318-25, 2010.
18.
Lim, M. C., Kang, S., Song, Y. J., Park, S. H., and Park, S. Y. Feasibility and
safety of extensive upper abdominal surgery in elderly patients with advanced epithelial
ovarian cancer. J Korean Med Sci, 25: 1034-40, 2010.
19.
Lee, J. Y., Jung, D. C., Park, S. H., Lim, M. C., Seo, S. S., Park, S. Y., and
Kang, S. Preoperative prediction model of lymph node metastasis in endometrial cancer.
Int J Gynecol Cancer, 20: 1350-5, 2010.
20.
Kim, S. H., Kang, S., Kim, Y. M., Kim, B. G., Seong, S. J., Cha, S. D., Park,
C. Y., and Yun, Y. H. Prevalence and predictors of anxiety and depression among
cervical cancer survivors in Korea. Int J Gynecol Cancer, 20: 1017-24, 2010.
21.
Kim, K. W., Choi, H. J., Kang, S., Park, S. Y., Jung, D. C., Cho, J. Y., Cho,
K. S., and Kim, S. H. The utility of multi-detector computed tomography in the diagnosis
of malignant pleural effusion in the patients with ovarian cancer. Eur J Radiol, 75: 230-5,
2010.
22.
Kim, H. S., Park, N. H., Kang, S., Seo, S. S., Chung, H. H., Kim, J. W., Song,
Y. S., and Kang, S. B. Comparison of the efficacy between topotecan- and belotecan-, a
new camptothecin analog, based chemotherapies for recurrent epithelial ovarian cancer: a
single institutional experience. J Obstet Gynaecol Res, 36: 86-93, 2010.
23.
Kang, S., Kim, T. J., Nam, B. H., Seo, S. S., Kim, B. G., Bae, D. S., and Park,
S. Y. Preoperative serum CA-125 levels and risk of suboptimal cytoreduction in ovarian
cancer: a meta-analysis. J Surg Oncol, 101: 13-7, 2010.
24.
Kang, S., Kim, S. K., Chung, D. C., Seo, S. S., Kim, J. Y., Nam, B. H., and
Park, S. Y. Diagnostic value of (18)F-FDG PET for evaluation of paraaortic nodal
metastasis in patients with cervical carcinoma: a metaanalysis. J Nucl Med, 51: 360-7,
2010.
25.
Kang, S., Dong, S. M., and Park, N. H. Frequent promoter hypermethylation
of TGFBI in epithelial ovarian cancer. Gynecol Oncol, 118: 58-63, 2010.
26.
Jung, D. C., Kim, M. K., Kang, S., Seo, S. S., Cho, J. Y., Park, N. H., Song,
Y. S., Park, S. Y., Kang, S. B., and Kim, J. W. Identification of a patient group at low
risk for parametrial invasion in early-stage cervical cancer. Gynecol Oncol, 119: 426-30,
2010.
27.
Jung, D. C., Kang, S., Kim, M. J., Park, S. Y., and Kim, H. B. Multidetector
CT predictors of incomplete resection in primary cytoreduction of patients with advanced
ovarian cancer. Eur Radiol, 20: 100-7, 2010.

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28.
Song, Y. J., Lim, M. C., Kang, S., Seo, S. S., Park, J. W., Choi, H. S., and
Park, S. Y. Total colectomy as part of primary cytoreductive surgery in advanced
Mullerian cancer. Gynecol Oncol, 114: 183-7, 2009.
29.
Shin, D. W., Ahn, E., Kim, Y. M., Kang, S., Kim, B. G., Seong, S. J., Cha, S.
D., Park, C. Y., and Yun, Y. H. Cross-cultural application of the Korean version of the
European Organization for Research and Treatment of Cancer quality of life
questionnaire cervical cancer module. Oncology, 76: 190-8, 2009.
30.
Park, J. Y., Bae, J., Lim, M. C., Lim, S. Y., Lee, D. O., Kang, S., Park, S. Y.,
Nam, B. H., and Seo, S. S. Role of high risk-human papilloma virus test in the follow-up
of patients who underwent conization of the cervix for cervical intraepithelial neoplasia. J
Gynecol Oncol, 20: 86-90, 2009.
31.
Lim, M. C., Lee, D. O., Kang, S., Seo, S. S., Lee, B. Y., and Park, S. Y.
Clinical manifestations in patients with ovarian clear cell carcinoma with or without
co-existing endometriosis. Gynecol Endocrinol, 25: 435-40, 2009.
32.
Lim, M. C., Kim, T. J., Kang, S., Bae, D. S., Park, S. Y., and Seo, S. S.
Embryonic natural orifice transumbilical endoscopic surgery (E-NOTES) for adnexal
tumors. Surg Endosc, 23: 2445-9, 2009.
33.
Lim, M. C., Kang, S., Seo, S. S., Kong, S. Y., Lee, B. Y., Lee, S. K., and
Park, S. Y. BRCA1 and BRCA2 germline mutations in Korean ovarian cancer patients. J
Cancer Res Clin Oncol, 135: 1593-9, 2009.
34.
Lim, M. C., Kang, S., Lee, K. S., Han, S. S., Park, S. J., Seo, S. S., and Park,
S. Y. The clinical significance of hepatic parenchymal metastasis in patients with
primary epithelial ovarian cancer. Gynecol Oncol, 112: 28-34, 2009.
35.
Lim, M. C., Kang, S., Choi, J., Song, Y. J., Park, S., Seo, S. S., and Park, S.
Y. Hyperthermic intraperitoneal chemotherapy after extensive cytoreductive surgery in
patients with primary advanced epithelial ovarian cancer: interim analysis of a phase II
study. Ann Surg Oncol, 16: 993-1000, 2009.
36.
Kong, S. Y., and Kang, S. Epstein-Barr virus-transformation of B-cell lines in
ovarian cancer patients: feasibility of genomic storage for unlimited use. J Gynecol
Oncol, 20: 243-5, 2009.
37.
Kitchener, H. C., and Trimble, E. L. Endometrial cancer state of the science
meeting. Int J Gynecol Cancer, 19: 134-40, 2009.
38.
Kim, S. K., Choi, H. J., Park, S. Y., Lee, H. Y., Seo, S. S., Yoo, C. W., Jung,
D. C., Kang, S., and Cho, K. S. Additional value of MR/PET fusion compared with
PET/CT in the detection of lymph node metastases in cervical cancer patients. Eur J
Cancer, 45: 2103-9, 2009.
39.
Kim, M., Lim, M. C., Seo, S. S., Kang, S., Kim, S. K., and Park, S. Y.
Unusual 2-[18F]-fluoro-2-deoxy-D-glucose accumulation induced by postoperative
intestinocutaneous fistula in the patient with uterine cervical cancer and SLE. Arch
Gynecol Obstet, 280: 141-4, 2009.
40.
Kang, S., Seo, S. S., and Park, S. Y. Nadir CA-125 level is an independent
prognostic factor in advanced epithelial ovarian cancer. J Surg Oncol, 100: 244-7, 2009.
41.
Kang, S., and Nam, B. H. Does neoadjuvant chemotherapy increase optimal
cytoreduction rate in advanced ovarian cancer? Meta-analysis of 21 studies. Ann Surg
Oncol, 16: 2315-20, 2009.

- 5 -

42.
Bae, J., Seo, S. S., Park, Y. S., Dong, S. M., Kang, S., Myung, S. K., and
Park, S. Y. Natural history of persistent high-risk human papillomavirus infections in
Korean women. Gynecol Oncol, 115: 75-80, 2009.
43.
Bae, J., Lim, M. C., Choi, J. H., Song, Y. J., Lee, K. S., Kang, S., Seo, S. S.,
and Park, S. Y. Prognostic factors of secondary cytoreductive surgery for patients with
recurrent epithelial ovarian cancer. J Gynecol Oncol, 20: 101-6, 2009.
44.
Rho, S. B., Dong, S. M., Kang, S., Seo, S. S., Yoo, C. W., Lee, D. O., Woo, J.
S., and Park, S. Y. Insulin-like growth factor-binding protein-5 (IGFBP-5) acts as a
tumor suppressor by inhibiting angiogenesis. Carcinogenesis, 29: 2106-11, 2008.
45.
Park, J. Y., Lee, K. H., Dong, S. M., Kang, S., Park, S. Y., and Seo, S. S. The
association of pre-conization high-risk HPV load and the persistence of HPV infection
and persistence/recurrence of cervical intraepithelial neoplasia after conization. Gynecol
Oncol, 108: 549-54, 2008.
46.
Lim, M. C., Kim, J. Y., Kim, T. H., Park, S., Kong, S. Y., Yoon, J. H., Kang,
S., Seo, S. S., and Park, S. Y. Allogeneic blood transfusion given before radiotherapy is
associated with the poor clinical outcome in patients with cervical cancer. Yonsei Med J,
49: 993-1003, 2008.
47.
Lim, M. C., Bae, J., Park, J. Y., Lim, S., Kang, S., Seo, S. S., Kim, J. Y., Rho,
J. W., and Park, S. Y. Experiences of pretreatment laparoscopic surgical staging in
patients with locally advanced cervical cancer: results of a prospective study. J Gynecol
Oncol, 19: 123-8, 2008.
48.
Kang, S., Seo, S. S., and Park, S. Y. Occult para-aortic lymph node
metastasis after negative positron emission tomography/computed tomography scan. J
Clin Oncol, 26: 5140; author reply 5140-1, 2008.
49.
Kang, S., Dong, S. M., Seo, S. S., Kim, J. W., and Park, S. Y. FAS -1377
G/A polymorphism and the risk of lymph node metastasis in cervical cancer. Cancer
Genet Cytogenet, 180: 1-5, 2008.
50.
Jung, D. C., Ju, W., Choi, H. J., Kang, S., Park, S., Yoo, C. W., and Park, S.
Y. The validity of tumour diameter assessed by magnetic resonance imaging and gross
specimen with regard to tumour volume in cervical cancer patients. Eur J Cancer, 44:
1524-8, 2008.
51.
Park, J. Y., Lee, S. M., Yoo, C. W., Kang, S., Park, S. Y., and Seo, S. S. Risk
factors predicting residual disease in subsequent hysterectomy following conization for
cervical intraepithelial neoplasia (CIN) III and microinvasive cervical cancer. Gynecol
Oncol, 107: 39-44, 2007.
52.
Kang, S., Kim, J. W., Park, N. H., Song, Y. S., Park, S. Y., Kang, S. B., and
Lee, H. P. Interleukin-1 beta-511 polymorphism and risk of cervical cancer. J Korean
Med Sci, 22: 110-3, 2007.
53.
Kang, S., Kim, H. S., Seo, S. S., Park, S. Y., Sidransky, D., and Dong, S. M.
Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in
cervical adenocarcinoma. Gynecol Oncol, 105: 662-6, 2007.
54.
Jo, H., Kang, S., Kim, S. I., Kim, J. W., Park, N. H., Song, Y. S., Park, S. Y.,
Kang, S. B., and Lee, H. P. The C19007T polymorphism of ERCC1 and its correlation
with the risk of epithelial ovarian and endometrial cancer in Korean women. A case
control study. Gynecol Obstet Invest, 64: 84-8, 2007.

- 6 -

55.
Jo, H., Kang, S., Kim, J. W., Kang, G. H., Park, N. H., Song, Y. S., Park, S.
Y., Kang, S. B., and Lee, H. P. Hypermethylation of the COX-2 gene is a potential
prognostic marker for cervical cancer. J Obstet Gynaecol Res, 33: 236-41, 2007.
56.
Park, J. Y., Seo, S. S., Kang, S., Lee, K. B., Lim, S. Y., Choi, H. S., and Park,
S. Y. The benefits of low anterior en bloc resection as part of cytoreductive surgery for
advanced primary and recurrent epithelial ovarian cancer patients outweigh morbidity
concerns. Gynecol Oncol, 103: 977-84, 2006.
57.
Kang, S., Lee, J. M., Jeon, E. S., Lee, S., Kim, H., Kim, H. S., Seo, S. S.,
Park, S. Y., Sidransky, D., and Dong, S. M. RASSF1A hypermethylation and its inverse
correlation with BRAF and/or KRAS mutations in MSI-associated endometrial
carcinoma. Int J Cancer, 119: 1316-21, 2006.
58.
Kang, S., Kim, M. H., Park, I. A., Kim, J. W., Park, N. H., Kang, D., Yoo, K.
Y., Kang, S. B., Lee, H. P., and Song, Y. S. Elevation of cyclooxygenase-2 is related to
lymph node metastasis in adenocarcinoma of uterine cervix. Cancer Lett, 237: 305-11,
2006.
59.
Kang, S., Kim, J. W., Kang, G. H., Lee, S., Park, N. H., Song, Y. S., Park, S.
Y., Kang, S. B., and Lee, H. P. Comparison of DNA hypermethylation patterns in
different types of uterine cancer: cervical squamous cell carcinoma, cervical
adenocarcinoma and endometrial adenocarcinoma. Int J Cancer, 118: 2168-71, 2006.
60.
Kang, S., Ju, W., Kim, J. W., Park, N. H., Song, Y. S., Kim, S. C., Park, S. Y.,
Kang, S. B., and Lee, H. P. Association between excision repair cross-complementation
group 1 polymorphism and clinical outcome of platinum-based chemotherapy in patients
with epithelial ovarian cancer. Exp Mol Med, 38: 320-4, 2006.
61.
Choi, H. J., Lee, J. H., Seok Lee, J., Choi, J. I., Kang, S., Lee, S., Seo, S. S.,
and Park, S. Y. CT findings of clear cell carcinoma of the ovary. J Comput Assist
Tomogr, 30: 875-9, 2006.
62.
Choi, H. J., Lee, J. H., Kang, S., Seo, S. S., Choi, J. I., Lee, S., and Park, S. Y.
Contrast-enhanced CT for differentiation of ovarian metastasis from gastrointestinal tract
cancer: stomach cancer versus colon cancer. AJR Am J Roentgenol, 187: 741-5, 2006.
63.
Choi, H. J., Kim, S. H., Seo, S. S., Kang, S., Lee, S., Kim, J. Y., Kim, Y. H.,
Lee, J. S., Chung, H. H., Lee, J. H., and Park, S. Y. MRI for pretreatment lymph node
staging in uterine cervical cancer. AJR Am J Roentgenol, 187: W538-43, 2006.
64.
Kang, S., Roh, J. W., and Kim, J. W. Single nucleotide polymorphism: a new
risk factor for endometrial cancer? Future Oncol, 1: 323-30, 2005.
65.
Kang, S., Kim, Y. B., Kim, M. H., Yoon, K. S., Kim, J. W., Park, N. H., Song,
Y. S., Kang, D., Yoo, K. Y., Kang, S. B., and Lee, H. P. Polymorphism in the nuclear
factor kappa-B binding promoter region of cyclooxygenase-2 is associated with an
increased risk of bladder cancer. Cancer Lett, 217: 11-6, 2005.
66.
Kang, S., Kim, J. W., Park, N. H., Song, Y. S., Kang, S. B., and Lee, H. P.
Cyclin D1 polymorphism and the risk of endometrial cancer. Gynecol Oncol, 97: 431-5,
2005.
67.
Kang, S., Kim, J. W., Kang, G. H., Park, N. H., Song, Y. S., Kang, S. B., and
Lee, H. P. Polymorphism in folate- and methionine-metabolizing enzyme and aberrant
CpG island hypermethylation in uterine cervical cancer. Gynecol Oncol, 96: 173-80,
2005.

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68.
Ju, W., Kang, S., Kim, J. W., Park, N. H., Song, Y. S., Kang, S. B., and Lee,
H. P. Promoter polymorphism in the matrix metalloproteinase-1 and risk of cervical
cancer in Korean women. Cancer Lett, 217: 191-6, 2005.
69.
Choi, Y. S., Kim, Y. H., Kang, S., Jeon, Y. T., Kim, J. W., Park, N. H., Song,
Y. S., Kang, S. B., and Lee, H. P. Feasibility of radical surgery in the management of
elderly patients with uterine cervical cancer in Korea. Gynecol Obstet Invest, 59: 165-70,
2005.
70.
Jeon, Y. T., Kang, S., Kang, D. H., Yoo, K. Y., Park, I. A., Bang, Y. J., Kim,
J. W., Park, N. H., Kang, S. B., Lee, H. P., and Song, Y. S. Cyclooxygenase-2 and p53
expressions in endometrial cancer. Cancer Epidemiol Biomarkers Prev, 13: 1538-42,
2004.

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