MDMA pdf.pdf

While there is good evidence that CYP2D6 is the primary metabolic pathway for MDMA,
hydroxlyation is possible at all 3 ring positions. Interestingly, CYP3A4 inhibition would lead to
lower levels of ring-hydroxlated MDA metabolites, which I think (largely due to their similarity to
6-hydroxydopamine) are more likely candidates for neurotoxicity than the corresponding MDMA
metabolites.