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Adrenal gland .pdf



Original filename: Adrenal gland.pdf
Title: Slide 1
Author: Nasima

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The Adrenals Glands
Prof. AKM Musa

Cushing’s syndrome

• Cushing’s syndrome is caused by excessive activation
of glucocorticoid receptors.
• It is most commonly iatrogenic,
due to prolonged administration of synthetic
glucocorticoids such as prednisolone
(even inhaled or topical ).

• Both Cushing’s disease and cortisol-secreting adrenal
tumours are 4 times more common in women than
men.
• In Cushing’s disease, the pituitary tumour is usually a
microadenoma
• A careful drug history taking is a must.


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