PDF Archive

Easily share your PDF documents with your contacts, on the Web and Social Networks.

Share a file Manage my documents Convert Recover PDF Search Help Contact



Seronegative Arthropathy .pdf



Original filename: Seronegative Arthropathy.pdf
Title: Slide 1
Author: user

This PDF 1.5 document has been generated by Microsoft® PowerPoint® 2013, and has been sent on pdf-archive.com on 20/05/2017 at 17:30, from IP address 45.127.x.x. The current document download page has been viewed 204 times.
File size: 1.1 MB (68 pages).
Privacy: public file




Download original PDF file









Document preview


Seronegative
Spondyloarthropathy

Dr. Jamal Uddin Ahmed
Assistant Professor, Internal Medicine
BIRDEM & IMC

Dx ?






30 yrs male
Low back pain
Morning stiffness
CRP – 48
Xray SI joint – B/L sacroilitis

What are these?
• A group of related inflammatory joint diseases
• Considerable overlap in their clinical features
• Shared immunogenetic association with the
HLA-B27 antigen

These are






Ankylosing spondylitis
Axial spondyloarthritis
Reactive arthritis, including Reiter’s syndrome
Psoriatic arthritis
Arthropathy associated with inflammatory
bowel disease.

Etiology
• Aberrant response to infection
• In genetically predisposed individuals.
In some situations, a triggering organism can
be identified, as in reactive arthritis following
bacterial dysentery or chlamydial urethritis,

Clinical features common to seronegative
spondyloarthritis
• Asymmetrical inflammatory oligoarthritis (lower > upper
limb)
• Sacroiliitis and inflammatory spondylitis
• Inflammatory enthesitis
• Tendency for familial aggregation
• RF and ACPA negative
• Absence of nodules and other extra-articular features of
RA
• Typical overlapping extra-articular features:

Typical overlapping extra-articular features:
 Mucosal inflammation: conjunctivitis, buccal
ulceration,
 Urethritis, prostatitis, bowel ulceration
 Pustular skin lesions and nail dystrophy
 Anterior uveitis
 Aortic root fibrosis (aortic incompetence, conduction
defects)
 Erythema nodosum

Ankylosing Spondylitis

• The prototype of the spondyloarthropathies.
• Marie-Strumpell disease or Bechterew's
disease.


Related documents


seronegative arthropathy
us drug companies need competition
rheumatoid arthritis
ibd imc nazmul
remyduboisscheapnewswith2daydietjapan
how to get rid of arthritis pain


Related keywords