PDF Archive

Easily share your PDF documents with your contacts, on the Web and Social Networks.

Share a file Manage my documents Convert Recover Search Help Contact



Acute pancreatitis nazmul mbbs student .pdf



Original filename: Acute pancreatitis_nazmul mbbs student.pdf
Title: Acute Pancreatitis
Author: user

This PDF 1.5 document has been generated by Microsoft® PowerPoint® 2013, and has been sent on pdf-archive.com on 25/05/2017 at 18:31, from IP address 45.127.x.x. The current document download page has been viewed 114 times.
File size: 2 MB (68 pages).
Privacy: public file




Download original PDF file









Document preview


Acute Pancreatitis

Definitions
• The 1992 Atlanta Symposium definition of acute
pancreatitis, which is “”An acute inflammatory process of
the pancreas with variable involvement of other regional
tissues or remote organ systems”

Criteria for DX

The diagnosis of AP is most oft en established by the
presence of 2 of the 3 following criteria:
1. Abdominal pain consistent with the disease,
2. Serum amylase and / or lipase greater than three
times the upper limit of normal, and / or
3. Characteristic findings from abdominal imaging
( USG/CT/MRI)

Pathogenesis
of Acute Pancreatitis
Three
theories of pathogenesis:
• Auto digestion theory.
• Obstructive theory.
• Reflux theory.

Pathogenesis of Acute Pancreatitis
Activation of Pancreatic enzymes :
Several recent studies have suggested that

Pancreatitis is a disease that evolves in three
phases:

1st phase: Intrapancreatic digestive enzyme (e.g. Zymogene)
activation and acinar cell injury.
2nd Phase: Activation, chemo attraction and sequestration of
neutrophils in the pancreas resulting in an intrapancreatic
inflammatory reaction of variable severity.
3rd phase: due to the effects of activated proteolytic enzymes
(e.g. Trypsin) and mediators released by inflammed
pancreas on distant organs. Trypsin not only digests
pancreatic tissue but also activates other enzymes such
as elastase and phospholipase.


Related documents


PDF Document acute pancreatitis nazmul mbbs student
PDF Document chr pancreatitis complications
PDF Document get help with pancreatitis symptoms1576
PDF Document protocols list clinical research program
PDF Document chief of dept of gi at action cancer hospital
PDF Document general info concerning diabetic issues1701


Related keywords