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RESEARCH REPORT
Nov - 2017
BLOOD BRAIN BARRIER TECHNOLOGIES MARKET
SEGMENTED BY DISTRIBUTION CHANNEL, AND BY END USER ANALYSIS, SIZE, SHARE,
GROWTH, TRENDS AND FORECASTS 2016-2021

Global Blood Brain Barrier Technologies

The Global Blood Brain Barrier Technologies market size was around USD XX billion in 2016.
It is expected to grow at a CAGR of XX% to reach USD XX billion by 2021.
Brain is one of the largest and most intricate organs in the human body. It consists of 100
billion nerves that communicate with a 100 trillion synapses. It is made up of midbrain,
hindbrain, and forebrain. It is responsible for movement and thought produced by the body.
It has its own security system-a filtering mechanism consisting of blood vessels which allow
entry of essential nutrients at the same time blocking other substances-known as the bloodbrain barrier. Blood-brain barrier is a semi-permeable dynamic interface which separates
the capillaries which carry blood to the brain and spinal cord tissue by blocking the passage
of certain substances. It is formed by highly specialized endothelial cells. The vessels of the
blood-brain barrier are made up of specialized endothelial cell which line brain capillaries
from the vascular system which lack fenestration of pores and allow rapid exchange of
molecules between vessels and tissues. The blood-brain barrier protects the neural tissue
from harmful chemicals and maintains a stable environment. However, this barrier is so
effective at blocking the entry of foreign substances that it often prevents penetration of
life-saving drugs to address issues like injuries and diseases. Therefore, discovery of new
methods allowing the effective delivery of drugs and bio-macromolecules to the central
nervous system (CNS) is of immense importance for the treatment of neurodegenerative
disorders. Neurodegeneration and neuro inflammation are major events in CNS disorders
like Parkinson's disease, stroke, Alzheimer's disease, and multiple sclerosis. But still, the
drugs for CNS treatment, like neurotrophic factors, including BDNF, EPO (erythropoietin),
and anti-inflammatory antibodies (e.g., Enbrel and Remicade), do not cross the blood-brain
barrier in effective therapeutic quantities.
Growing prevalence of neurological diseases like Parkinson’s disease, meningitis, multiple
sclerosis, and encephalitis, augmenting geriatric population, rising healthcare expenditure,
increasing investment in R&D for the development of new drugs and delivery devices,
growing awareness about healthcare, and rising number of initiatives by various
governments and affiliated associations are few key factors driving the growth of the
On the other hand, intricate regulatory frameworks for the approval of drugs in most
countries and inordinate approval time for drugs due to the insufficient knowledge of the
brain are primary restraints for the growth of the market.
By geography the market is segmented into North America, Asia Pacific, Latin America,
Europe and Middle East and Africa. North America leads the global market given the
increasing incidence of neurological diseases and augmenting geriatric population in the
region. Asia is anticipated to show high growth rates in the forecast period in the market,
with China and India being the fastest growing markets in Asia Pacific. The primary driving
forces for the market in emerging economies are the large pool of patients, growing
awareness about the disease, improving healthcare infrastructure, and increasing
government funding in the region.
Key players in the market are Bristol-Myers Squibb Company, Pfizer, Inc., biOasia
Technologies, Inc., Cypress Biosciences, Inc., Janssen Pharmaceutical N.V., Teva

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Global Blood Brain Barrier Technologies

Pharmaceuticals Industries, Ltd., F. Hoffmann La-Roche, Ltd., Eli Lilly and Company, FabreKramer Pharmaceuticals, Inc., NeuroVive Pharmaceutical AB, and ArmaGen

Table of Content
1. Introduction
1.1 Market Definition
1.2 Study Deliverables
1.3 Base Currency, Base Year and Forecast Periods
1.4 General Study Assumptions
2. Research Methodology
2.1 Introduction
2.2 Research Phases
2.2.1 Secondary Research
2.2.2 Primary Research
2.2.3 Econometric Modelling
2.2.4 Expert Validation
2.3 Analysis Design
2.4 Study Timeline
3. Overview
3.1 Executive Summary
3.2 Key Inferences
3.3 Epidemology
4. Drivers, Restraints, Opportunities, and Challenges Analysis (DROC)
4.1 Market Drivers
4.2 Market Restraints
4.3 Key Challenges
4.4 Current Opportunities in the Market
5. Market Segmentation
5.1 Geography
5.1.1 Introduction
5.1.2 North America

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Global Blood Brain Barrier Technologies

5.1.3 Latin America
5.1.4 Europe
5.1.5 Asia Pacific
5.1.6 Middle East and Africa
5.1.7 Y-o-Y Growth Analysis, By Geography
5.1.8 Market Attractiveness Analysis, By Geography
5.1.9 Market Share Analysis, By Geography
6. Geographical Analysis
6.1 Introduction
6.1.1 Regional Trends
6.1.2 Impact Analysis
6.1.3 Y-o-Y Growth Analysis
6.1.3.1 By Geographical Area
6.1.4 Market Attractiveness Analysis
6.1.4.1 By Geographical Area
6.1.5 Market Share Analysis
6.1.5.1 By Geographical Area
6.2 North America
6.1.1 Introduction
6.1.2 United States
6.1.3 Canada
6.3 Europe
6.2.1 Introduction
6.2.2 U.K
6.2.3 Spain
6.2.4 Germany
6.2.5 Italy
6.2.6 France
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Global Blood Brain Barrier Technologies

6.4 Asia-Pacific
6.3.1 Introduction
6.3.2 China
6.3.3 India
6.3.4 Japan
6.3.5 Australia
6.3.6 South Korea
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6.5 Latin America
6.4.1 Introduction
6.4.2 Brazil
6.4.3 Argentina
6.4.4 Mexico
6.4.5 Rest of Latin Before
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6.6 Middle East & Africa
6.5.1 Introduction
6.5.2 Middle-East
6.5.3 Africa
7. Strategic Analysis
7.1 PESTLE analysis
7.1.1 Political
7.1.2 Economic
7.1.3 Social
7.1.4 Technological
7.1.5 Legal
7.1.6 Environmental
7.2 Porter’s Five analysis
7.2.1 Bargaining Power of Suppliers

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Global Blood Brain Barrier Technologies

7.2.2 Bargaining Power of Consumers
7.2.3 Threat of New Entrants
7.2.4 Threat of Substitute Products and Services
7.2.5 Competitive Rivalry within the Industry
8. Market Leaders' Analysis
8.1 Allon Therapeutics, Inc.
8.1.1 Overview
8.1.2 Product Analysis
8.1.3 Financial analysis
8.1.4 Recent Developments
8.1.5 SWOT analysis
8.1.6 Analyst View
8.2 AngioChem Inc.
8.3 Genzyme
8.4 CeNeRx BioPharma, Inc
8.5 Bioasis Technologies Inc.
8.6 Ablynx NV
8.7 Capsulution Pharma AG
8.8 International Brain Barriers Society (IBBS)
8.9 Cephalon Inc
8.10 Cognition Pharmaceuticals LLC
9. Competitive Landscape
9.1 Market share analysis
9.2 Merger and Acquisition Analysis
9.3 Agreements, collaborations and Joint Ventures
9.4 New Product Launches
10. Market Outlook and Investment Opportunities
Appendix
a) List of Tables
b) List of Figures

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Global Blood Brain Barrier Technologies

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SCOPE OF THE REPORT

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Global Blood Brain Barrier Technologies



Regional and country-level analysis and forecasts of the study market; providing
Insights on the major countries/regions in which this industry is blooming and to also
identify the regions that are still untapped



Segment-level analysis in terms of technology, component, and type along with
market size forecasts and estimations to detect key areas of industry growth in detail



Identification of key drivers, restraints, opportunities, and challenges (DROC) in the
market and their impact on shifting market dynamics



Study of the effect of exogenous and endogenous factors that affect the global
market; which includes broadly demographic, economics, and political, among other
macro-environmental factors presented in an extensive PESTLE Analysis



Study the micro environment factors that determine the overall profitability of an
Industry, using Porter’s five forces analysis for analyzing the level of competition
and business strategy development



A comprehensive list of key market players along with their product portfolio,
current strategic interests, key financial information, legal issues, SWOT analysis and
analyst overview to study and sustain the market environment



Competitive landscape analysis listing out the mergers, acquisitions, collaborations
in the field along with new product launches, comparative financial studies and
recent developments in the market by the major companies



An executive summary, abridging the entire report in such a way that decisionmaking personnel can rapidly become acquainted with background information,
concise analysis and main conclusions



Expertly devised analyst overview along with Investment opportunities to provide
both individuals and organizations a strong financial foothold in the market

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