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Programme Details and Delegate Profiles.pdf

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Professor Paul Townsend
Associate Dean Business Engagement, Faculty of Biology,
Medicine and Health

Professor Townsend is a York graduate (1993) and read for his PhD at Imperial Cancer Research Fund (now Cancer
Research UK) central laboratories in London (1997), followed by post-doctoral work at Imperial College London, with
research experience in the US and Germany followed by a Wellcome Trust Fellowship at UCL (2001-2004). He was
made Faculty staff in 2004 at the University of Southampton, initially funded by Wellcome and BBSRC, full Professor
in 2009, Associate Director of Enterprise & Innovation, and Deputy Director of the Cancer Research UK Centre before
relocating to Manchester in early 2013 as Associate Dean for Business Engagement & Enterprise. In 2015 he
developed and took on leadership of the International Research role for FBMH.
In the Faculty he chairs the Finance Committee, helping manage >£200M of funds. He is also Faculty Chair and AD of
the University Business Engagement Strategy Group and University Business Engagement Group and member of the
Research Strategy Group amongst other roles including entrepreneurship and strategic/ infrastructure leadership.
He is the University industry and research lead for our £28.5M Biomedical Research Centre, incorporating
coordinated leadership with Health Innovation Manchester, Innovate UK, especially the Medicines Discovery
Catapult and strategic partner lead for large stakeholders e.g. AZ and Waters.
Professor Townsend is passionate about research and impact. He is research active, generating >£11M in career
research/innovation & enterprise income. He has been awarded funding from the UK Research Councils BBSRC, MRC,
EPSRC, and the European Union, as well as from a number of charities, industries and philanthropy. He maintains a
strong track record of publications having an H index of 41 including recent papers in Aging Cell and Nature Cell
Biology. The global reputation of his research is reflected by continued invitations to present at UK and international
conferences as well as contributing to RCUK committees, including BBSRC Committees C and D and BBSRC
Technology Research and Development Fund committee and reviewing for international agencies such as WeHi and
Peter Mac in Australia, NIH in the US, Hong Kong, A*STAR, Portugal, Pasteur Institute in France, and HRB in Ireland.
Professor Townsend has research strengths in cell stress and survival mechanisms, bioengineering, drug discovery,
validation, senescence, DNA damage, and epigenetics and multiple ‘omics in cancer biology, and apoptosis
regulation. His group has made impact and several important discoveries in these fields. Highlights include the
discovery that senescence can be assessed in real time and also in archival material, the role of p21 in DNA damage,
TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells; identifying the
stress activated role of stem cell transcription factor Oct4 in cell fate decisions and cell cycle modulators ARF and
MKK7 as DNA damage response modulators; dissecting the mechanism of urocortin as novel regulator of Piezo1
activity in the bone:prostate cancer axis; and the demonstration of senescence and advanced MS in biomarker
discovery, translation in disease and identifying novel regulators of cellular homeostasis.
His lab has generated a number of international, industry impacts and research activities, attracting philanthropic
and industry-funded projects supporting cell stress & biomarker research. Additionally, he has 6 separate SMErelated projects as well as being PI for Faculty industrial CASE studentships. This has helped lead to collaborative
applications and funding from Innovate UK, BBSRC and MRC and successful iCASE and Doctoral Training studentships
and CRUK/MCRC funding. Finally, Professor Townsend helps oversee the UoM-A*STAR research alliance and ‘cancer’
links with Brazil, India, Australia and China.
E-mail: paul.townsend@manchester.ac.uk