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Scientific Meeting of the Irish Thoracic Society (ITS) 2014 .pdf

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Irish Thoracic Society Annual Scientific Meeting 2014
7th–8th November 2014
Radisson Blu Hotel,

Irish Journal of Medical Science
Volume 183 Supplement 11
DOI 10.1007/s11845-014-1196-y



Ir J Med Sci (2014) 183 (Suppl 11):S483–S542

The Irish Thoracic Society thanks the following companies for their generous support, in the form of unrestricted
educational grants, of the 2014 Annual Scientific Meeting:
The Irish Thoracic Society Guest Lecture I and Oral and Poster Awards
Supported by an unrestricted educational grant from Boehringer Ingelheim Ireland

The Irish Thoracic Society Debate on Lung Cancer Screening
Supported by an unrestricted educational grant from Boston Scientific

The Irish Thoracic Society Guest Lecture II
Supported by an unrestricted educational grant from Vertex

The Irish Thoracic Society SpR Study Day and Case Study Forum
Supported by an unrestricted educational grant from Astra Zeneca

The Irish Thoracic Society Update Lecture
Supported by an unrestricted educational grant from Intermune UK and Ireland

Irish Thoracic Society Meeting Programme
Supported by an unrestricted educational grant from

Irish Thoracic Society Meeting Delegate Bag
Supported by an unrestricted educational grant from
Baywater Healthcare

Irish Thoracic Society Drinks Reception
Supported by BOC Healthcare

The ANAIL Forum
Supported by an unrestricted educational grant from
Mundipharma Pharmaceuticals


Ir J Med Sci (2014) 183 (Suppl 11):S483–S542


Exhibitors at the Irish Thoracic Society Annual Scientific Meeting 2014

Pharmaceutical and Medical Device Suppliers
InterMune UK and Ireland
Actelion Pharmaceuticals UK Ltd
A Menarini Pharmaceuticals Ireland
Astra Zeneca
Bayer HealthCare
Baywater Healthcare
BOC Healthcare
Boehringer Ingelheim
Boston Scientific
Cardiac Services Group
Direct Medical Ltd
Eurosurgical Ltd
Forest Laboratories UK Ltd
Home Healthcare Ltd

Meda Health Sales Ireland Ltd
Medicare Health and Living Ltd
Mundipharma Pharmaceuticals Ltd
Novartis Ireland Ltd
Orion Pharma (Ireland) Ltd
Pfizer Healthcare Ireland (Anti-infectives)
Pfizer Healthcare Ireland (Champix)
Pharmaxis Pharmaceuticals Ltd
RespiCare Ltd
Sword Medical Ltd
Teva Pharmaceuticals Ireland
Vertex Pharmaceuticals (UK) Ltd

Patient Charities
The Alpha One Foundation
The Asthma Society of Ireland
COPD Support Ireland
Cystic Fibrosis Ireland
The Irish Cancer Society
The Irish Hospice Foundation
The Irish Lung Fibrosis Association
The Irish Sarcoidosis Support Network
The Irish Sleep Apnoea Trust



Ir J Med Sci (2014) 183 (Suppl 11):S483–S542

Disclosure Statement
The operational costs of the Irish Thoracic Society Annual Scientific Meeting 2014 are funded with the support of a number of commercial
bodies through unrestricted educational grants. These are listed overleaf.


Ir J Med Sci (2014) 183 (Suppl 11):S483–S542


Welcome from the Local Organisers
It is our great pleasure to welcome you to Galway, host to the 2014 Irish Thoracic Society Annual Scientific Meeting.
Following from a hugely successful meeting in Derry in 2013, we are delighted to see the meeting’s return to the City of the Tribes and have
put together a programme that reflects the best of respiratory medicine and healthcare and offers ‘state of the art’ education on a range of topics.
Thank you to all those who submitted abstracts and case studies this year—almost 200 in all—reflecting the high quality and innovative work
taking place in clinical and research centres throughout the island. We would also like to thank the abstract review committee and judges for their
time and expertise in what is never an easy task due to the increasingly high standard of submissions received.
The meeting will feature a combination of clinical and molecular research including: a presentation on use of patient data in clinical decisions
by Prof Martin Tobin, Loyola University of Chicago; an update on the treatment of IPF by Prof Jim Egan; a pro-con debate on lung cancer
screening featuring international experts Prof James Jett from National Jewish Health in Denver and Dr Cyrus Daneshvar, Plymouth University
Hospitals, and a presentation on information technology and healthcare by Dr Ronan Kavanagh.
Welcome also to the patient and professional organisations represented. Networking and sharing information on the wealth of activities taking
place across the respiratory healthcare community has become an integral part of the meeting.
Finally we would like to extend a particular welcome to the exhibitors and sponsors of this year’s meeting. We are very grateful for their
continued support.
Yours sincerely,

Prof Anthony O’Regan

Dr Robert Rutherford
Local Organisers, ITS Annual Scientific Meeting 2014



Ir J Med Sci (2014) 183 (Suppl 11):S483–S542

President’s Welcome
On behalf of the Irish Thoracic Society, I am delighted to welcome you to the ITS Annual Scientific Meeting 2014. I would like to take this
opportunity to update you on the work of the Society over the past 12 months particularly in the areas of education, research, advocacy and
public health.
Advocacy and Public Health
The ITS continues to play a central role in the work of the Irish Lung Health Alliance in raising awareness of lung disease amongst policy makers
and the public. A series of public lectures, delivered by ITS members, patient representatives, and guest speakers took place throughout the
country in late 2013. These were very well received and generated broad media coverage. Thanks to all those involved in making the campaign a
success and to Boehringer Ingelheim Ireland for their support. To coincide with the ERS ‘Healthy Lungs for Life’ campaign in September 2014,
the Alliance organised a nationwide awareness and public health campaign in conjunction with the Irish Institute of Clinical Measurement
Science (IICMS) Faculty of Respiratory, Glasgow Science Centre and supported by GSK. The initiative, which was launched by Minister for
Health, Mr Leo Varadkar, saw a Lung Health Roadshow incorporating the BodyWorks On Tour Exhibition and Free Lung Testing visit a number
of key locations throughout Ireland, including Portlaoise, Ireland’s Healthy Town 2014.
2014 saw the introduction and approval of the Standardised Packaging of Tobacco Legislation—a vital step in protecting future generations of
Irish children against tobacco related illness. The ITS actively supported this measure through our work as part of the Health Charities Coalition
and our attendance at the Committee Hearings of the Joint Oireachtas Committee for Health and Children. We were very pleased to play an
advocacy role in progressing this essential legislation. Also on the theme of tobacco and public health we are planning a Symposium on Smoking
and Pregnancy to take place on the 18th November in conjunction with the TobaccoFree Research Institute (TRI) and the Royal College of
Physicians of Ireland (RCPI). This will be based on research carried out by the TRI and presented at this meeting in previous years which shows
the high prevalence of smoking in pregnancy, the health implication for babies born to mothers who smoke and the lack of smoking cessation
services for pregnant women. This poses a serious public health challenge which we feel needs to be highlighted.
Thanks to the support of Allen and Hanburys, Boehringer Ingelheim and Novartis, through unrestricted educational grants, the Irish Thoracic
Society has been able to continue offering much needed funding for research in respiratory medicine. We are pleased to report that we have once
again been successful in securing joint funding through the MRCG HRB Joint Funding Scheme 2014. The successful grant is titled ‘Investigating
the impact of bile aspiration on chronic respiratory disease: Chronic infection—Bile Paradigm led by Prof Fergal O’Gara, UCC with coapplicants Dr Muireann Ni Chroinin and Dr David Mullane. This was the result of a highly competitive and rigorous grant review process.
Thanks to the support of our partners and participation in the joint funding scheme we have been able to offer grants for research in respiratory
medicine to the total value of €320,000.00 over the past 3 years.
The ITS Spring Meeting 2014 took place in Kinsale in April. This meeting was held in conjunction with the Cork Respiratory Faculty and
featured ‘State of the Art’ lectures from key national and international experts. This was an outstanding event and many thanks to Boehringer
Ingelheim for their support through an unrestricted educational grant.
A key initiative under development in 2014 and into 2015 will be the establishment of Irish Thoracic Society Registry for Interstitial Lung
Disease. This promises to provide much needed data on the prevalence, distribution, and longitudinal follow up of patients with IPF and other
ILD in Ireland and may have applications to other respiratory diseases into the future. Thanks to Boehringer Ingelheim Ireland for their support
on this initiative.
Finally, a very special feature of this year’s meeting will take place as part of the Gala Dinner on Friday evening when it will be a great
honour to present the Irish Thoracic Society Award for Outstanding Contribution to Respiratory Medicine to a very deserving and highly
respected recipient who has contributed greatly to Respiratory Medicine in Ireland and beyond over a long career.
The success of all these initiatives is only possible thanks to the support and engagement of our members, partner organisations and our
partners from the pharmaceutical and medical equipment sectors. This support is hugely appreciated and we look forward to continued
collaboration in 2015 and beyond.
Have a great meeting!

Professor Anthony O’Regan
President, the Irish Thoracic Society


Ir J Med Sci (2014) 183 (Suppl 11):S483–S542


Thursday 6th November

Specialist Registrar (SpR) Training—Veranda Lounge
Supported by Astra Zeneca through an unrestricted educational grant


ITS Case Study Forum—followed by dinner and prize for Best Case Presentation 2014—Inis Mor Suite 2 and 3
Supported by Astra Zeneca through an unrestricted educational grant


MX FitzGerald, UCD
JJ Gilmartin, Galway University Hospitals


Case Study Poster Review—Inis Mor Suite 2 and 3


Case Study Oral Presentations—Inis Mor Suite 2 and 3


1. A case of a forgotten disease post tonsillectomy
M Ahmed, S Ahmed, W Shah, B Cushen, B Canavan, C McGurk
St Luke’s Hospital, Kilkenny, Ireland


2.‘White out’ of Lung
RP Cusack1, CG O’Leary1, LJ Chawke1, J McCarthy2, DR Curran1, TM O’Connor1
Departments of 1Respiratory Medicine and 2Gastroenterology, Mercy University Hospital, Cork


3. An unusual cause of Massive Haemoptysis
Kelly R, O’Reilly K, Redmond K, Lawler L, Eaton D
Departments of Thoracic Surgery, Respiratory Medicine and Radiology, Mater University Hospital, Dublin 7


4. Leading up the Garden Path?
Moore I, Chapman N, Polley L, Convery R
Craigavon Area Hospital, Southern Health and Social Care Trust


5. Rare case of Persistent Cough
Thong L1, Khan KA1, O’Connor TM2, Kennedy MP1
Cork University Hospital/University College Cork, 2Mercy University Hospital Cork


Dinner and Prize-giving

Friday 7th November

Registration, tea and coffee, exhibition viewing—Inis Mor Suite


Poster Review and Parallel Discussions


Poster Review—Inis Mor Suite 2 and 3 and Veranda Lounge


Parallel Poster Discussions
1. Asthma and Sleep—Inis Mor Suite 2


J. Faul, Connolly Hospital, Dublin
JJ. Gilmartin, Galway University Hospitals, Galway
2. COPD Clinical—Inis Mor Suite 3


K. Finan, Sligo Regional Hospital, Co Sligo
M. Sheehy, Midland Regional Hospital, Mullingar, Co Westmeath
3. General Respiratory—Veranda Lounge


T. McDonnell, St Vincent’s University Hospital Dublin
M. Rogan, University Hospital Waterford, Co Waterford



Ir J Med Sci (2014) 183 (Suppl 11):S483–S542


4. Interstitial Lung Disease and Rarer Respiratory Disorders—Marinas Private Section
D. O’Callaghan, Mater Misericordiae University Hospital, Dublin
C. Rooney, Mayo General Hospital, Castlebar, Co Mayo


Tea and Coffee/Exhibition viewing—Inis Mor Suite


Oral Presentations I—Inis Mor Suite 2 and 3


T. O’Connor, Mercy University Hospital Cork, Cork
S. Donnelly, Adelaide and Meath Hospital (incorporating the National Children’s Hospital, Tallaght, Dublin 24


5.1. High prevalence of Non-Smoking related Obstructive Lung Disease in Farmers in Ireland
B Cushen1, N Donoghue2, D Langan1, T Cahill1, E Nic Dhonnacha1, O Healy1, F Keegan1, M Browne3, I Sulaiman4, A O’Regan1
Department of Respiratory Medicine, Galway University Hospital
Department of Respiratory Medicine, Bon Secours Hospital, Galway
NUI Galway
Royal College of Surgeons in Ireland


5.2. Positional Therapy is a Cheap and Effective Alternative to Continuous Positive Airway Pressure in PositionAssociated Obstructive Sleep Apnoea
DB Fitzgerald, LJ Chawke, JS O’Sullivan, M Rafferty, A O’Mahony, TM O’Connor, DR Curran
Department of Sleep and Pulmonary Medicine, Mercy University Hospital, Cork


5.3. Inflammatory induced ER stress in Cystic Fibrosis neutrophils is reduced by ivacaftor treatment
White M, Alfawaz B, Cox S, Hayes E, McElvaney NG, and Reeves EP
Royal College of Surgeons, Ireland


5.4. Serum exosomes from IPF patients display a fibrotic miRNA profile and induce collagen production in vitro
Rosemary Kane1*, Robert V. Lumsden1*, Sharon Whitty1, Denise Boylan1, Sinead Walsh1,2, Julie Worrell1, Faheem Khan 1,2,
Seamas C Donnelly1,2, Marcus Butler 1,2, Aurelie Fabre 1,2, Michael P. Keane1,2
UCD Conway Institute of Biomolecular and Biomedical research, University College Dublin, Belfield, Dublin 4, Ireland. 2
Department of Respiratory Medicine, St Vincent’s University Hospital and School of Medicine and Medical Science, UCD
Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland


5.5. Patient Experience of Pirfenidone Use at a Specialist ILD Clinic
Subramaniam A, Elshafi M, Thong L, O’Halloran K, Bowen B, Khan KA, Murphy DM, Plant BP, Kennedy MP, Henry MT
Department of Respiratory Medicine, Cork University Hospital


5.6. 100 Lung Transplants Delivered In Ireland
Gough A, Wood AE, McCarthy JF, Nolke L, Healy DG, Redmond K, Eaton DR, Javadpour H, Egan JJ
National Thoracic Transplantation Service, Mater Misericordiae University Hospital, Dublin 7, Ireland


ITS Guest Update—Inis Mor Suite 2 and 3
Supported by InterMune UK and Ireland through an unrestricted educational grant
Pharmacological treatment of IPF in 2014
Prof Jim Egan, Consultant Respiratory Physician, Mater Misericordiae University Hospital

Parallel Business Meetings/Forums
Friday 7th November

Primary Ciliary Dyskinesia Round Table Discussion—Joyce Suite


Forum of ANAIL—Association of Irish Nurses in Respiratory Care—Morris Suite
Supported by Mundipharmaceuticals Ltd through an unrestricted educational grant


Forum of the IICMS Faculty of Respiratory (formerly IARS)—Joyce Suite


Forum of Chartered Physiotherapists in Respiratory Care—Darcy Suite


Irish Thoracic Society Paediatric Forum—Veranda Lounge


COPD Outreach Meeting—Veranda Lounge


Ir J Med Sci (2014) 183 (Suppl 11):S483–S542



6. Irish Thoracic Society Paediatric Forum—Veranda Lounge
D. Slattery, Children’s University Hospital, Temple St, Dublin


6.1 Paediatric Respiratory Non-invasive ventilation service
Carrig C, Devitt M, McDonald M, Greally P
Paediatric Respiratory Department, Tallaght Hospital, Dublin 24


6.2 Heated Humidified High Flow Nasal Cannualtion (HHHFNC) Therapy in the Treatment of Bronchiolitis
F Kennedy, D Finn, B Elnazir
Paediatric Dept., AMNCH Tallaght, Dublin


6.3. A Comparative study of two medication groups of infants with moderate bronchiolitis
F.Yasin, Z.S.Afridi, R.Khan
Paediatric Department, Kerry General Hospital Tralee, Ireland


6.4. Life-threatening post-fontan plastic bronchitis: a paediatric case report and literature review
Tee WJ1, Franklin O2, Cox DW1
Respiratory Department, Our Lady’s Children’s Hospital, Crumlin, Dublin, Ireland
Cardiology Department, Our Lady’s Children’s Hospital, Crumlin, Dublin, Ireland


6.5. The effects of vitamin D supplementation on pulmonary function, disease severity and markers of inflammation in
childhood asthmatics: a randomized, double-blind, placebo-controlled trial
CP. Kerley1,2, K. Hutchinson3 P. Greally4, D. Coghlan4 and B. Elnazir4
Unversity College, Dublin, Belfield, Dublin 4
Respiratory and Sleep Diagnostics Department, Connolly Hospital, Dublin 15
Biomnis Ireland, Sandyford business Estate, 3 Rock Rd, Dublin
The Adelaide and Meath Hospital, Dublin


6.6. Comparison of Two Methods of Inhaler Technique Instruction in Children
S Arthurs, R Khan, F Yasin, E Cahalane, J Cournane, B Browne and R O’Shea
Physiotherapy and Paediatric Departments, Kerry General Hospital


6.7. 5 Year Review of First Time Colonisations of Pseudomonas Aeruginosa in Children with Cystic Fibrosis: Treatment
and Outcomes
D Finn, G Leen, B Elnazir,
Respiratory Dept, AMNCH, Tallaght


6.8. Determing the lung clearance index of children with cystic fibrosis, aged 4–16 versus healthy subjects in an irish
Keane L1, Linnane B2, Saunders J3,4, Zeugolis, D5
1 Centre for Adult Learning and Professional Development,
2 University Hospital Limerick,
3 Statistical Consulting Unit, University of Limerick,
4 Centre for Support and Training in Analysis and Research CSTAR Limerick,
5 Network of Excellence for Functional Biomaterials, National University of Ireland


6.9 Mycobacterium africanum and disseminated TB in childhood: a case illustrating a rare presentation in the
immunocompetent host
S Giva1, S Geoghegan1, C Hickey2, C Bogue3, TM O’Connor4, D Mullane1, SM O’Connell1
Departments of 1Paediatrics and Child Health, 2Microbiology and 3Radiology, Cork University Hospital and 4Department of
Respiratory Medicine, Mercy University Hospital


Irish Thoracic Society Paediatric Forum Guest Lecture
A bluffer’s guide to Primary Antibody Deficiency
Dr Ronan Leahy, Consultant in Paediatric Immunology and Infectious Diseases, Our Lady’s Children’s Hospital,
Crumlin and Children’s University Hospital, Temple St. Honorary Senior Lecturer, Royal College of Surgeons in Ireland


Meeting of ITS Paediatric Special Advisory Panel


Lunch—Marinas Restaurant


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