Changn SH Notes.pdf


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SH
Epidemiology of HIV/AIDs .................................................................................................................. 3
Behavioural research in HIV transmission: ........................................................................................... 9
Lymphatic structure and organs: ......................................................................................................... 12
Lymphocytes: ..................................................................................................................................... 17
Immune responses: ............................................................................................................................. 21
Overview of respiratory function: ....................................................................................................... 26
Respiratory mechanics: ....................................................................................................................... 32
Gas laws and partial pressure: ............................................................................................................. 41
Oxygen uptake, transport and blood flow: .......................................................................................... 46
CO2 exchange and transport ............................................................................................................... 53
Control of respiration: ......................................................................................................................... 58
Haem and haemoglobin ...................................................................................................................... 65
Respiration and acid-base balance: ..................................................................................................... 73
Ventilation/perfusion and exercise: ..................................................................................................... 79
Hypoxia – causes and adaption: .......................................................................................................... 85
Transmission of infection: .................................................................................................................. 92
Microorganisms and disease pathogenesis: ......................................................................................... 99
Infection and pathology in the immunocompromised host: .............................................................. 103
Opportunistic infections in HIV: ....................................................................................................... 106
Drug delivery and distribution – introduction to pharmacokinetics: ................................................. 110
Pharmacokinetic calculations: ........................................................................................................... 115
Pharmacokinetics – 2 compartments: ................................................................................................ 119
Respiratory development .................................................................................................................. 122
Upper respiratory tract anatomy: ...................................................................................................... 128
Lower respiratory tract anatomy ....................................................................................................... 143
Respiratory histology: ....................................................................................................................... 150
Musculoskeletal anatomy of the chest wall: ...................................................................................... 154
Immunology of HIV: ........................................................................................................................ 166
Antivirals: ......................................................................................................................................... 174
Influenza: .......................................................................................................................................... 181
Vaccination: ...................................................................................................................................... 185
Scenario plenary: influenza and swine flu ........................................................................................ 188
Global health: ................................................................................................................................... 189
Lower respiratory tract infections: .................................................................................................... 191
Surveillance: ..................................................................................................................................... 197
Pneumonia: pathology: ..................................................................................................................... 200