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ESH

EUROPEAN
SCHOOLOF
HAEMATOLOGY

INTERNATIONAL CONFERENCE ON
AGING AND HEMATOLOGICAL MALIGNANCIES:
BIOLOGY AND THERAPY
Athens, Greece
March 11-13,2016
Chairs: Lodovico Balducci, Pierre Fenaux, Michael Hallek, Bob Lowenberg

Friday, March 11,2016
8:15-8:30: Welcome

SESSION I - Aging: The Setting
Chair: Lodovico Balducci (Tampa)
8:30-9:00 The biology of aging: insights into causes of
aging-associated diseases and implications for human health
9:00-9:10 Discussion

Bjorn Schumacher (Cologne)

9:10-9:25
Phannacological aspects in the older individual
9:25-9:30 Discussion

Claire Falandry (Lyon)

9:30-9:45
Geriatric assessment
9:45-9:50 Discussion

Ulrich Wedding (Jena)

9:50-10:05 Decision making in older patients
10:05-10:10 Discussion

Lodovico Balducci (Tampa)

10:10-10:40 Round Table Discussion
10:40-11:10 Coffee Break and Poster Viewing

SESSION II - Hematopoiesis in the Aging Individual
Chair: Pierre Fenaux (Paris)
11:10-11:25 Aging of the hematopoietic system
11:25-11:30 Discussion

Gerald de Ilaan (Groningen)

11:30-11:45 Causes and consequences of immunosenescence
11:45-11:50 Discussion

Graham Pawelec (Tubingen)

11:50-12:20 Round Table Discussion
12:20-14:00 Lunch

SESSION III - How to Treat? : Acute Leukemia
Chair: Boh Lowenberg (Rotterdam)
14:00-14:15 Population data on the treatment of older patients with AML
14:15-14:20 Discussion

Gunnar Juliusson (Lund)

14:20-14:35 The leukemic stem cell
14:35-14:40 Discussion

Hind Medyouf (Frankfurt)

14:40-14:55 Clonal hematopoiesis and the risk of hematological malignancies
14:55-15:00 Discussion

Giulio Genovese (Cambridge)
Michael Heuser (Hannover)

15:00 -15:15 Molecular genetics in older patients with AML
15:15-15:20 Discussion
15:20-15:50 Round Table Discussion
15:50-16:20 Coffee Break and Poster Viewing
16:20-16:35 Treatment of older patients with ALL
16:35-16:40 Discussion

Jacob Rowe (Jerusalem)

16:40-16:55 Treatment of the older patients with AML with intensive chemotherapy
16:55-17:00 Discussion

Bob Lowenberg (Rotterdam)

17:00-17:15 Treatment of older patients with non-intensive treatment regimens
17:15-17:20 Discussion

Gerwin Huls (Groningen)

17:20-17:50 Round Table Discussion

Saturday, March 12,2016
8:00-9:00 3 Simultaneous Meet the Expert Sessions
1. How to use the relevant molecular biomarkers in AML
in the older patient with AML?

Gerwin Huls (Groningen)

2. Pharmacology of aging
3. Treating elderly CLL patients with reduced fitness

Claire Falandry (Lyon)
Michael Hallek (Cologne)

SESSION IV - Anemia in the Elderly
Chair: Eva Hellstrom-Lindberg (Stockholm)
9:15-9:30 Epidemiology of anemia at older age
9:30-9:35 Discussion
9:35-9:50 Clinical management of anemia in the elderly
9:50-9:55 Discussion
09:55-10:25 Round Table Discussion
10:25-10:55 Coffee Break and Poster Viewing

Wendy Den Elzen (Leiden)
Matteo Della Porta (Pavia)

SESSION V - How to Treat? : MDS/MPN
Chair: Pierre Fenaux (Paris)
10:55-11:10 Pre-leukemic progenitors
11:10-11:15 Discussion

Pctter Woll (Oxford)

11:15-11:30 The molecular biology of MDS
11:30-11:35 Discussion

Luca Malcovati (Pavia)

11:35-11:50 Prognostic factors in MDS and CMML
11:50-11:55 Discussion

Pierre Fenaux (Paris)

11:55-12:25 Round Table Discussion
12:25-13:55 Lunch
Eva Ilellstrom-Lindberg (Stockholm)
13:55-14:10 Anemia and thrombocytopenia:
treatment challenges in lower risk MDS in the elderly
14:10-14:15 Discussion
14:15-14:30 Treatment of higher risk MDS and CMML in the elderly
14:30-14:35 Discussion

Pierre Fenaux (Paris)

14:35-14:50 Biology and management of MPN in the elderly
14:50-14:55 Discussion

Radck Skoda (Basel)

14:55-15:10 Biology and management of CML in the elderly
15:10-15:15 Discussion

Andreas Ilochhaus (Jena)

15:15-15:45 Round Table Discussion
15:45-16:15 Coffee Break and Poster Viewing
SESSION VI - Transplants in Older Patients
Chair: Gunnar Juliusson (Lund)
16:15-16:30 Hematopoietic stem cell transplantation in the elderly
16:30-16:35 Discussion

Nikolaus Kroger (Hamburg)

16:35-17:05 General discussion

Michael Hallek (Cologne),
Eva Ilellstrom-Lindberg (Stockholm),
Gerwin Huls (Groningen)
Nikolaus Kroger (Hamburg)

17:05-18:05 Manned Poster Session

Sunday, March 13,2016
8:00-9:00

3 Simultaneous Meet the Expert Sessions

1. How to approach the older patient with a hematological malignancy:
the unique context and requirements

Jacob Rowe (Jerusalem)

2. Economic issues in the treatment of older patients with myeloma
3. Could we use the relevant molecular biomarkers in the practical
management of the older patient with diffuse large B-cell lymphoma?

Sara Bringhen (Turin)
Herve Tilly (Rouen)

SESSION VII - How to Treat ? : Lymphoma and Myeloma
Chairs: Michael Hallek (Cologne), Eva Kimhy (Stockholm)
9:15-9:30 Treatment of elderly frail patient with multiple myeloma
9:30-9:35 Discussion

Sara Bringhen (Turin)

9:35-9:50
9:50-9:55

Michael Hallek (Cologne)

Aspects of treating elderly patients with CLL
Discussion

9:55-10:10 Treating elderly patients with follicular lymphoma
10:10-10:15 Discussion

Eva Kimby (Stockholm)

10:15-10:45 Round Table Discussion
10:45-11:15 Coffee Break
11:15-11:30 Treating elderly patients with mantle cell lymphoma
11:30-11:35 Discussion

Herve Tilly (Rouen)

11:35-11:50 Treating elderly patients with DLBCL

Michael Pfrcundschuh (Homburg)

11:50-11:55 Discussion
11:55-12:10 Treatment of elderly patients with Hodgkin lymphoma
12:10-12:15 Discussion
12:15-12:45 Round Table Discussion
End of the meeting

Boris Boll (Cologne)


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