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Immune Repertoire Sequencing .pdf


Original filename: Immune Repertoire Sequencing.pdf
Title: Immune Repertoire Sequencingdy Services
Author: http://www.synbio-tech.com/services/antibody-service/immune-repertoire-sequencing/

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Immune Repertoire Sequencing

Immune Repertoire refers to the set of all functionally diversified B cells and T cells
in the circulatory system of an individual at any given time. Immune repertoire
sequencing (Immuno-Seq) targets at T/B lymphocytes and utilizes the 5’Rapid
Amplification of cDNA Ends (RACE) Technology. The 5’ RACE technology amplifies
complementarity-determining regions (CDRs) of B cell receptors (BCRs) or T cell
receptors (TCRs). The CDRs are targeted because they control the diversity of the
corresponding BCRs and TCRs. Combined with the high-throughput sequencing
technology, the Immuno-Seq provides a comprehensive evaluation of the immune
system diversity.
Synbio Technologies provides our customers with a complete antibody repertoire
sequencing system including immune repertoire sequencing, antibody CDR region
sequencing, etc. Our Immuno-Seq System is designed to assist researchers in the
observation and analysis of both T and B cells with unprecedented specificity. The
specificity allows the Immuno-Seq technology to be applied to disease surveillance,
antibody production, vaccine research, health examination and other related areas.

Advantages
 The robust RACE technology and specially optimized PCR amplification
systems designed to minimize the amplification bias of the immune repertoire
genes
 Diversified NGS analysis platform
 Optimal success rates and fast turnaround times
 Complete and advanced bioinformatic analysis designed to examine highly
valuable information

Contact us
Synbio Technologies
1 Deer Park Drive, Suite L-1
Monmouth Junction
NJ, 08852

Tel:+1 732-230-3003
Fax:+1 609 228 5911
Web:www.synbio-tech.com
E-mail:service@synbio-tech.com

Applications
 Health status examination through analysis of the immune/antibody repertoire
diversity
 Trace the development of antigen-specific antibodies and contribute to the
research being conducted on humanized antibodies
 Evaluation of the vaccine performance

Services Specifications
Service

Deliverables

Turnaround Time

Price

Immune Repertoire
Sequencing

1.NGS sequencing data
2.Bioinformatics
analysis report

6-8 Weeks

Inquiry

*For Immuno-Seq service: customers will need to submit one of the following: 1-2ml
peripheral blood, splenocyte, selected immune cells or extracted high quality RNA.

Contact us
Synbio Technologies
1 Deer Park Drive, Suite L-1
Monmouth Junction
NJ, 08852

Tel:+1 732-230-3003
Fax:+1 609 228 5911
Web:www.synbio-tech.com
E-mail:service@synbio-tech.com


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