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NGTMCodon Optimization Technology .pdf


Original filename: NGTMCodon Optimization Technology.pdf
Title: NGTMCodon Optimization Technology
Author: http://www.synbio-tech.com/services/gene-synthesis/ngcodon-optimization-technology/

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NGTMCodon Optimization Technology
NGTMCodon Optimization Technology
During the gene synthesis process, codon optimization is a method refers to the use
of preferred codons, that is, to avoid the rare codons with low utilization, to simplify
mRNA’s secondary structure after gene transcription, to remove the motif which is
not conducive to efficient expression and add the helpful one, to adjust the GC
content and other methods to re-design genes. The commercialization of gene
synthesis has greatly promoted the application scope and influence of codon
optimization. By the employment of NGTM Codon system, Synbio Technologies’
patent pending codon optimization algorithm, complex sequences are optimized
both efficient and free, thus obtain you a significant higher protein expression level.
Synbio Technologies can provide gene synthesis codon optimization service for free.

Advantages of NGTMCodon Optimization Technology
 Raise the protein expression level significantly.
 Gene synthesis codon optimization is available in any hosts:
Different organisms have their own preferred codons, for example the prioritized
termination codon of yeast and mammalian are UAA and UGA respectively. Specific
gene synthesis codon optimizations are applied for different organisms, Specific
codon optimizations are provided regard to the hosts that clients provided.
 Excellent results even in the most difficult sequences:
NGTM Codon optimization is capable of optimizing the most complex sequences
such as hairpin sequences, highly repeated sequences and extremely long
sequences.
 Intellectual property (IP) protection:
All of your IP related rights are fully protected by Synbio Technologies. The DNA
sequence and its related information are kept strictly confidential in the entire
process. All materials and mid-products including synthesized oligos, genes,
plasmids and the cells will be destroyed in one month after delivery.

Contact us
Synbio Technologies
1 Deer Park Drive, Suite L-1
Monmouth Junction
NJ, 08852

Tel:+1 732-230-3003
Fax:+1 609 228 5911
Web:www.synbio-tech.com
E-mail:service@synbio-tech.com

Case Studies

NGTMCodon improves codon usage efficiency. Y and X axis represent relative usage
frequency of codons and genetic codons, respectively. The codon usage (red lines)
was rather dispersed compared with the optimized one (green lines).Synbio
technologies has proprietary gene synthesis codon optimization system which can
satisfy different customers’ requirements.

Contact us
Synbio Technologies
1 Deer Park Drive, Suite L-1
Monmouth Junction
NJ, 08852

Tel:+1 732-230-3003
Fax:+1 609 228 5911
Web:www.synbio-tech.com
E-mail:service@synbio-tech.com


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