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an analysis of antidepressant medication data submitted to the US Food and Drug Administration.
Augmentation of the endocannabinoid system has been found to exhibit antidepressant and anxiogenic effects.
Adjunct Therapies and Self-Management Light therapy, yoga, physical activity, behavioural activation, sleep hygiene, and good nutrition can be effective complements to antidepressant medication or psychotherapy They can result in faster symptom improvement and fewer residual symptoms.
For example, in 2006 Carlos Zarate of the National Institute of Mental Health published a study demonstrating ketamine’s unusual antidepressant properties [see “Good News about Depression,” by Walter Brown;
Breast enlargement duringchronic antidepressant therapy.
Neurokinin-3-R agonism in aged rats has anxiolytic-, antidepressant-, and promnestic-like effects and stimulates ACh release in frontal cortex, amygdala and hippocampus.