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Using computational analyses, ChIP-Seq, RNA-Seq and high-throughput functional studies we are characterizing how genetic differences in regulatory sequences lead to clinical variation in drug response.
Though SEM and FIB-SEM have been very successful in characterizing the pore system in shale under low kV or VP mode on uncoated shale samples, their capability to characterize smaller pores down to the 3-5 nm size is still very challenging.
While the terms may contrast from industry to industry, the real stages normally take after basic strides to critical thinking—"characterizing the issue, measuring alternatives, picking a way, usage and assessment."
@UNC CS dMRI 87%
3 dMRI and mental disorders • dMRI used to identify location of stroke • Used in characterizing edema (Pasternak, 2009) • High b-value data was very sensitive to disease load in MS patients in characterizing normal appearing white matter (Cohen 2002) • Q-space sampling allows to characterize the fast and slow diffusing components which may belong to different tissue regions (AxCaliber – Assaf et al) • Diffusion Kurtosis Imaging (DKI) has been shown to be more sensitive to tissue changes (neurodevelopmental and in mild TBI) 4 Background - dMRI • Typically, diffusion tensor imaging is used in clinical settings (requires only 7 gradient directions).