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Discerning the relationship between testosterone and status DataBlitz Presentations 9:55am Keiko Ishii, Kobe University A polymorphism of serotonin 2A receptor (5-HT2AR) influences delay discounting 10:05am Rachel Grillot, University of California, Santa Barbara Cortisol as an endocrine signal of opposite-sex attraction 10:15am Joey Cheng, University of Illinois at Urbana-Champaign Prestige in a large-scale social group predicts longitudinal changes in testosterone 10:25am Chance Strenth, University of New Mexico Establishing time course of testosterone using saliva after a sublingual administration 10:35am Tanya Procyshyn, Simon Fraser University The endocrinology of empathy:
 Androgen Receptor The androgen receptor is a type of nucleus receptor that is activated by binding either of the androgenic hormones, testosterone, or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor.  Estrogen Receptor Estrogen receptors are a group of proteins found inside cells. They are receptors that are activated by the hormone estrogen (17βestradiol).  Steroids of the Endocrine System Hormones that affect change in the body by binding to cellular receptors. Cells are capable of changing their fundamental expression based on the type and quantity of hormones are attached to their receptors. Sex Steroids These hormones influence sexual evolution of the human form and support reproduction; these include androgens, estrogens, and progestogens. These are the hormones that signal primary and secondary sexual characteristics of our exterior selves as well as internal expressions of cellular growth and change over time. Corticosteroids Responsible for regulation of many aspects of the metabolism and immune function that help maintain blood volume and control renal excretion of electrolytes. Anabolic steroids Natural and synthetic, that interact with androgen receptors to increase muscle and bone synthesis. In popular expression, use of the term "steroids" often refers to anabolic steroids. These include Testosterone, Insulin, Androstenedione, and many exogenous compounds used for both medical, research, and athletic purposes; examples including Oxandrolone, Drostanolone, Oxymetholone, Methenolone, Boldenone, and many others. Core Elements of the Metabolic System Adenosine triphosphate (ATP) Often called the "molecular unit of currency" of intracellular energy transfer. ATP transports chemical energy within cells for metabolism. It is one of the end products of photophosphorylation, cellular respiration, and fermentation and used by enzymes and structural proteins in many cellular processes, including biosynthetic reactions, motility, and cell division.  Glutamine Glutamine is the most abundant amino acid (building block of protein) in the body. The body can make enough glutamine for its regular needs. But during times of extreme stress (the kind you experience after heavy exercise or an injury), your body may need more glutamine than it can make. Most glutamine is stored in muscles, followed by the lungs where much of the glutamine is made.  Cycles of the Metabolic Process Note: This is not a complete list. Alanine Cycle A glucose generating process involving the cycling of nutrients between skeletal muscle and the liver. When muscles degrade amino acids for energy needs, the resulting nitrogen is transaminated to pyruvate to form alanine. This alanine is shuttled to the liver where the nitrogen enters the urea cycle and the pyruvate is used to make glucose.  Gluconeogenesis A metabolic pathway that results in the generation of glucose from noncarbohydrate carbon substrates such as pyruvate, lactate, glycerol, and glucogenic amino acids.  Elements of the Metabolic Process Note: This is not a complete list.
Depression, low testosterone, and muscle pain are some of the common side effects and that are due to the mechanism of how these drugs work.
CP149719,CP148602 WELL MAN ULTRAVIT Test Result IRON T.I.B.C TRANSFERRIN SATURATION FERRITIN 27.47 66.87 41.08 102 Units Range BIOCHEMISTRY Iron Status umol/L umol/L % ug/L 10.60 41.00 20.00 30.00 mmol/L mmol/L mmol/L mmol/L nmol/L 0.00 0.00 0.90 0.00 0.00 33.54 % 20.00 - 100.00 THYROID STIMULATING HORMONE FREE THYROXINE 3.92 18.2 mIU/L pmol/L 0.27 - 4.20 12.00 - 22.00 PROSTATE SPECIFIC AG(TOTAL) PROSTATE SPECIFIC AG(FREE) FREE:TOTAL RATIO 0.389 0.168 0.43 ug/L ug/L 0.00 - 1.40 0.00 - 0.90 0.19 - 1.00 TESTOSTERONE 12 nmol/L 7.60 - 31.40 VITAMIN B12 FOLATE (SERUM) 25 OH VITAMIN D 158 3.88 54.5 pmol/L ug/L nmol/L 140.00 - 724.00 2.91 - 50.00 50.00 - 200.00 Cholesterol Status TRIGLYCERIDES CHOLESTEROL HDL CHOLESTEROL LDL CHOLESTEROL Non-HDL Cholesterol Heart Disease Risk HDL % OF TOTAL 1.43 4.8 *1.61 2.54 3.19 - – 28.30 77.00 55.00 400.00 2.30 4.99 1.50 3.00 3.99 ENDOCRINOLOGY Thyroid Function Prostate Screen Hormone HAEMATOLOGY Vitamins Interpretation of results:
decreased production of testosterone due to testes not responding to LH/FSH (or Eunuchs) -Can also be due to failure of Pituitary/HypoThal to secrete Lh/FSH -Decreased Body Hair, underdeveloped muscles/bones -decreased libido, Erectile Dysfunction, Infertility FULL THICKNESS/ SUBDERMAL BURN:
3alpha,17beta-dihydroxy-5alphaandrost-1-ene) 4000 III N 1-Androstenedione (5alpha-androst-1-en-3,17-dione) 4000 III N 3Alpha,17beta-dihydroxy-5alpha-androstane 4000 III N 3Beta,17beta-dihydroxy-5alpha-androstane 4000 III N 4-Androstenediol (3beta,17beta-dihydroxy-androst-4ene) 4000 III N 4-Androstenedione (androst-4-en-3,17-dione) 4000 III N 4-Dihydrotestosterone (17beta-hydroxyandrostan-3one) 4000 III N 4-Hydroxy-19-nortestosterone (4,17beta-dihydroxyestr4-en-3-one) 4000 III N 4-Hydroxytestosterone (4,17beta-dihydroxyandrost-4en-3-one) 4000 III N 5-Androstenediol (3beta,17beta-dihydroxy-androst-5ene) 4000 III N 5-Androstenedione (androst-5-en-3,17-dione) 4000 III N Anabolic steroids 4000 III N Androstanedione (5alpha-androstan-3,17-dione) 4000 III N Bolasterone (7alpha,17alpha-dimethyl-17betahydroxyandrost-4-en-3-one) 4000 III N Boldenone (17beta-hydroxyandrost-1,4-diene-3-one) 4000 III N Boldione 4000 III N Calusterone (7beta,17alpha-dimethyl-17betahydroxyandrost-4-en-3-one) 4000 III N Methosarb Clostebol (4-chloro-17beta-hydroxyandrost-4-en-3-one) 4000 III N Alfa-Trofodermin, Clostene, 4-chlorotestosterone Dehydrochloromethyltestosterone (4-chloro-17betahydroxy-17alpha-methylandrost-1,4-dien-3-one) 4000 III N Oral-Turinabol 17-Alpha-methyl-1-testosterone 4-AD Anabolex, Andractim, Pesomax, Stanolone "Body Building"
● They’re universal across human cultures ● They often have clear biological causes and links to prenatal testosterone ● Biological males that were castrated at birth and raised as females often still identify and act like males ● The underlying traits are highly heritable ● They’re exactly what we would predict from an evolutionary psychology perspective Note, I’m not saying that all men differ from all women in the following ways or that these differences are “just.” I’m simply stating that the distribution of preferences and abilities of men and women differ in part due to biological causes and that these differences may explain why we don’t see equal representation of women in tech and leadership.
Vitamin B12 Testosterone, Cardiac Risk Marker (Apo A1, Apo B, Homocysteine, LpA, hsCRP), Electrolytes Profile, Pancreas Profile ேமQக_ட பdேசாதைனகll ெசyய ேவ_1m.
Tweeden hit the stage and the already loud audience burst into a testosterone-induced din.
Dopaminergic and serotonergic activity in neostriatum and nucleus accumbens enhanced by intranasal administration of testosterone.
The hexane extract of saw palmetto has been identified as the active ingredient with predominantly antiandrogenic activity and in vivo estrogenic activity demonstrated in rats.80 Saw palmetto has also been shown to inhibit both dihydrotestosterone binding at the androgen receptors and 5-a-reductase activity on testosterone, both being mechanisms thought to be influential in the management of benign prostatic hypertrophy.81 In 2 double-blind trials both objective (eg, frequency of nocturia and urine flow rate) and subjective (eg, dysuria intensity and patient’s self-rating) data indicated significant (P,.01) improvement when saw palmetto (320 mg/d) was ARCH INTERN MED/ VOL 158, NOV 9, 1998 2203 Downloaded from www.archinternmed.com on June 23, 2011 ©1998 American Medical Association.